[D-Trp7,9,10]-Substance P ( —— )

产品货号. M30809 CAS No. 89430-38-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

[D-Trp7,9,10]-Substance P
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
产品描述

Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.
体外实验

Substance P (SP)-related peptide, pGlu-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2, inhibitS the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

——
研究领域

——
适应症

——

CAS Number

89430-38-6
分子量

1588.89
分子式

C79H105N21O13S
纯度

>98% (HPLC)
溶解度

water:1 mg/mL
SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O
化学全称

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1. Mukai et al (1992) G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J.Biol.Chem. 267 16237 PMID:

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